Castle Biosciences reported results for 2026 with revenue of $103.55M, up from $86.19M a year earlier, while net loss was ($2.06M) versus net income of $4.52M in the prior year and diluted EPS was ($0.07) compared with $0.15— according to the company's 10-Q filing.

Financial Highlights

MetricCurrent quarterPrior year quarterYoY changeRevenue¹$103.55M$86.19M20.1%Net income²($2.06M)$4.52M(145.5%)Diluted EPS³($0.07)$0.15(146.7%)

¹ Reported as “Net Revenues”. ² Reported as “Net (loss) income”. ³ Reported as “Diluted earnings per share”.

Business Highlights

  • Revenue growth was driven by expansion into non-dermatologic tests; TissueCypher contributed meaningfully as the company shifted channels, with non-dermatologic tests representing roughly 52% of revenue.
  • Test report volumes rose about 13% year to date; TissueCypher volumes increased approximately 61% YTD while DecisionDx‑Melanoma volumes were up about 9% YTD.
  • AdvanceAD‑Tx limited launch (November 2025) recorded roughly 1,650 orders YTD, indicating early clinician interest.
  • Operational investments included a Pittsburgh lab expansion and completion of the Friendswood headquarters, increasing TissueCypher capacity to meet demand.

Original SEC Filing:

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