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SRZN: Dual-targeting Wnt and VEGF therapies show synergistic efficacy in retinal disease models
The discussion highlighted the scientific rationale for targeting Frizzled-4 and Wnt signaling in retinal diseases, emphasizing the synergy of dual and tri-specific antibodies addressing VEGF, Wnt, and IL-6 pathways. Preclinical data show promise for improved fluid resolution and reperfusion, with…