The FTSE MIB fell 0.2% to close at 51,163 on Monday, with losses across most sectors.
Buzzi led the decline, dropping 4.8%, followed by Stellantis (-2.8%), Inwit (-2.6%), Nexi (-2.2%), and Amplifon (-1.6%).
Insurers also underperformed, with Unipol and Generali falling 1.7% and 1.4%, respectively.
Financial companies underperformed after the rebound in BTPs pressured banks' and insurers' balance sheets, with BPER, and Unipol dropping more than 1%.
Also, Intesa Sanpaolo dropped 0.9% after officializing its offer for MPS (-0.8%) under the Italian securities officials.
On the upside, Avio gained 2.7%, while DiaSorin added 2.4%.
Oil prices edged up following recent US-Iran tensions, prompting oil linked firms gains for Saipem (1.8%) and ENI (1.4%).
STMicroelectronics advanced 1.6% and Prysmian gained 1.3%, supported by a global AI rally after last week's sell-off.
Meanwhile, the market focus will be on ECB's Sintra Forum over the coming days.