Arcturus Therapeutics entered a strategic collaboration with Thermo Fisher to advance ARCT-032, its investigational mRNA therapy for cystic fibrosis. The Master Services Agreement provides up to $40 million in clinical manufacturing services from Thermo Fisher, alongside up to $40 million in CRO services via PPD. Thermo Fisher will gain exclusive commercial manufacturing rights upon approval of ARCT-032, to be detailed in a future supply agreement. A related Project Addendum with Patheon covers tech transfer, clinical supply manufacturing, fill-finish, release, and stability work to support development and potential commercialization.

Agreement 1: Arcturus Therapeutics, Thermo Fisher Strike ARCT-032 CRO/CDMO MSA: $40M Mfg + $40M CRO

  • Agreement type: Master Services Agreement for CRO and CDMO collaboration on ARCT-032
  • Counterparty: Thermo Fisher Scientific
  • Signed / Effective: Jun 26 2026 / same
  • Duration / Termination: 5 years, auto-renews annually
  • Reason: Advance ARCT-032 development with integrated CRO and CDMO support

Agreement 2: Arcturus and Patheon Sign ARCT-032 Development Addendum Covering Tech Transfer and Clinical Supply

  • Agreement type: Project Addendum for Development Services (manufacturing and related activities)
  • Counterparty: Patheon UK
  • Signed / Effective: Jun 26 2026 / same
  • Duration / Termination: Until completion of services
  • Reason: Prepare ARCT-032 for clinical and commercial readiness

Original SEC Filing:

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