Warner Bros. Discovery's 'Supergirl' raked in $38 million in its U.S. opening weekend, disappointing already muted expectations, Benchmark analyst Matthew Harrigan says in a note. The film would need to gross about $450 million to $500 million globally to breakeven, though now it looks like its final box office run could actually fall below $200 million, the analyst says, noting weak ratings on CinemaScore and Rotten Tomatoes. "This suggests a potential $150M loss on the release," Harrigan says. Harrigan attributes some of the film's disappointing box office performance to the casting of Australian actress Milly Alcock, which garnered negative reactions among some fans, he says. "Superhero movies are notoriously sensitive to bad casting decisions, especially for female lead films that have often empirically been more difficult to market," he said. ([email protected])