Merck & Co., Inc. (NYSE:MRK) reported ISL/LEN combo met noninferior viral suppression at Week 48 with no new safety signals, cut royalty-free licenses for once-monthly alimatravir in 129 low-income countries, and expanded trials of Spevatamig with Keytruda plus chemo in biliary tract cancer.

Previous Week Recap

  • Merck & Co., Inc. Islatravir Noninferior Week 48: Merck's islatravir (MK-8591) with Gilead's lenacapavir (ISL/LEN) showed noninferior viral suppression at Week 48 in ISLEND-1/2; 0% vs 0.3% ≥50 copies/mL in ISLEND-1; no new safety issues.
  • MRK Licenses For Alimatravir To Generics: Merck (MRK) struck royalty‑free licenses with seven generics to allow manufacture and supply of once‑monthly HIV pill alimatravir in 129 low and lower‑middle‑income countries, pending approvals
  • MRK Phanes Spevatamig Keytruda Collaboration: Merck (MRK) expanded a clinical collaboration with Phanes to evaluate Spevatamig plus Keytruda and chemo in biliary tract cancer, covering trial cooperation and study drug supply.

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